Published July 1983
by Springer-Verlag .
Written in English
|The Physical Object|
|Number of Pages||236|
Wittig Chemistry. Conference proceedings. Citations; 3 Mentions; (TOPCURRCHEM, volume ) Papers Table of contents (5 papers) About About these proceedings; Table of contents. Search within book. Front Matter. PDF. Penta- and hexaorganyl derivatives of the main group five elements Angle strain Chemistry Protein Wittig-Reaktion. Wittig Chemistry: Dedicated to Professor Dr. G. Wittig (Topics in Current Chemistry ()) Softcover reprint of the original 1st ed. Edition by H. J. Bestmann (Contributor) ISBN ISBN Why is ISBN important? ISBN. This bar-code number lets you verify that you're getting exactly the right version or edition Author: Michael J. Krische, Christopher A. Hunter, Kendall Houk. The Wittig reaction or Wittig olefination is a chemical reaction of an aldehyde or ketone with a triphenyl phosphonium ylide (often called a Wittig reagent) to give an alkene and triphenylphosphine oxide. The Wittig reaction was discovered in by Georg Wittig, for which he was awarded the Nobel Prize in Chemistry in Exploring the Wittig Reaction: A Collaborative Guided-Inquiry Experiment for the Organic Chemistry Laboratory. Journal of Chemical Education , 91 (5), DOI: /ed Layne A. Morsch, Leanne Deak, Dyllan Tiburzi, Harrison Schuster, and Brittney by: 5.
Wittig Reaction: Alkenes from Carbonyl Compounds Study Questions 1) Why is it important that the aldehydes added to the ylide be free of carboxylic acids? (Hint: consider what a proton will do if added to the ylide.) Answer: Because the acidic proton on the carboxylic acid will protonate the negatively charged carbon, destroying the Size: 48KB. ISBN: OCLC Number: Description: 1 online resource (ix, pages) Contents: Penta- and hexaorganyl derivatives of the main group five elements --Enantioselective synthesis of nonproteinogenic amino acids --Selected topics of the wittig reaction in the synthesis of natural products --Industrial applications of the wittig reaction --Angle strained cycloalkynes. The reaction of an aldehyde or ketone with a phosphonium ylide to an alkene and a phosphine oxide is known as Wittig reaction or Wittig Olefination reaction.. This reaction was discovered in by Georg Wittig, for which he was awarded the Nobel Prize in Chemistry in * The yields of di- and tri-substituted alkenes from aldehydes and ketones are very high but yields of tetra-substituted. Marco Appel, Steffen Blaurock and Stefan Berger, A Wittig Reaction with 2‐Furyl Substituents at the Phosphorus Atom: Improved (Z) Selectivity and Isolation of a Stable Oxaphosphetane Intermediate, European Journal of Organic Chemistry, , 7, (), ().Cited by:
The Nobel Prize in Chemistry was awarded jointly to Herbert C. Brown and Georg Wittig "for their development of the use of boron- and phosphorus-containing compounds, respectively, into important reagents in organic synthesis". Early work on the 1,2-Wittig rearrangement was mechanistically inspired. As indicated in Table 2, yields of products tended to be moderate and harsh conditions were often effects of structural variation on reaction rates and product composition can be accommodated by a pathway involving homolysis of an α-anion intermediate and recombination of the radical and radical anion. The Wittig reaction produces Z alkenes. A variation of the Wittig reaction, called the Horner-Wadsworth-Emmons (HWE) reaction gives E alkenes. The mechanism of the HWE reaction resembles that of the Wittig reaction. We will discuss the mechanism in greater detail in Chap when we discuss the chemistry of hydrogens that are α to carbonyl. Review from previous edition: "If you want a really good book about organic chemistry get Organic Chemistry by Clayden, Greeves, Warren and Wothers." Nick is a Cambridge graduate, obtaining his PhD there in for work on the stereoselective Horner-Wittig reaction with Stuart Warren. He then held a Harkness Fellowship at the University of /5(43).